Hypnotic Effect of Ocimum basilicum on Pentobarbital-Induced Sleep in Mice

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Hypnotic Effect of Ocimum basilicum on Pentobarbital-Induced Sleep in Mice

BACKGROUND Sleep disorders are accompanied by several complications, and currently used soporific drugs can induce unwanted effects such as psychomotor impairment, tolerance, amnesia, and rebound insomnia. OBJECTIVES The present study was carried out to investigate if Ocimum basilicum has a sleep-prolonging effect. MATERIALS AND METHODS This work was an experimental study on 72 mice which w...

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hypnotic effect of ocimum basilicum on pentobarbital-induced sleep in mice

background sleep disorders are accompanied by several complications, and currently used soporific drugs can induce unwanted effects such as psychomotor impairment, tolerance, amnesia, and rebound insomnia. results hae increased the duration of pentobarbital-induced sleep at doses of 25, 50, and 100 mg/kg (p < 0.001). the hypnotic effect of hae was comparable to that induced by diazepam. similar...

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hypnotic effect of nepeta glomerulosa on pentobarbital-induced sleep in mice

background insomnia or sleeplessness is a disorder characterized by a personal incapability to falling or staying asleep for a desirable period of time, therefore disturb in quality of life. objectives the present study was carried out to investigate the effect of hydro-alcoholic extract of nepeta glomerulosa and its fractions on sleep-prolonging. materials and methods the extract and its fract...

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Effect of Methanolic Leaf Extract of Ocimum basilicum L. on Benzene-Induced Hematotoxicity in Mice

The aim of the present study was to investigate the protective role of methanolic leaf extract of Ocimum basilicum L. against benzene-induced hematotoxicity in Swiss albino mice. GC analysis and subacute toxicity level of the extract were tested. Mice were randomly divided into three groups among which II and III were exposed to benzene vapour at a dose 300 ppm × 6 hr/day × 5 days/week for 2 we...

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ژورنال

عنوان ژورنال: Iranian Red Crescent Medical Journal

سال: 2016

ISSN: 2074-1804,2074-1812

DOI: 10.5812/ircmj.24261